Page 18 - OxyBand Research Background

OxyBand Dressing Accelerates Wound Healing

During follow up visits, the dressings were removed, and wounds assessed for
pain, redness and exudate on a scale of 1-5 comparing the red and blue sides. The

percentage epithelialization (0% to 100%) was estimated by the physicians, and

wounds were marked and photographed. New dressings were applied on both sides
and the process was repeated until wounds were 100% epithelialized.

A final evaluation for assessment of scar appearance was performed at 30 days.
Upon enrollment, subjects were given instructions for participating in the study that

included “not to remove or detach the dressings” and “to contact the clinical trial staff if

the dressings detached from over the wounds at any time.” Subjects who did not comply
with instructions or schedules were discontinued from the study.

RESULTS:

The first study demonstrated the efficacy of OxyBand TM wound dressings in a
standardized wound compared to Tegaderm wound dressing over 7 days. In all
TM
cases, the un-epithelialized lesion size (mm) of the wounds treated with OxyBand was
TM
reduced significantly compared to the lesion size of the wounds treated with

TM
Tegaderm as measured with calipers. Results in Table 1 show the area of wound
TM TM
2
2
epithelialized by day 3 were 12.80 mm for OxyBand and 4.98 mm for Tegaderm
2
treated wounds, and by day 7 the un-epithelialized regions remaining were 1.79 mm for
TM TM
OxyBand and 5.51mm for Tegaderm . On day three, 2.6 times more wound area
2
TM
had epithelialized by the OxyBand treatments, and by day seven the standard of care
TM
Tegaderm treated wounds had 3.2 times more un-epithelialized area than the
OxyBand treated wounds. Further analysis showed a mean reduction in wound
TM
diameter of the OxyBand treated wounds by 1.37 mm + 0.68 at p < .001 compared to
TM
the Tegaderm treated wounds on day three. OxyBand treated wounds
TM
TM
demonstrated a significantly greater reduction in mean diameter by 3.49 mm + 0.27 at p
< .001 on day seven compared to the Tegaderm treated wounds (Photos IA & IB).
TM

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