Page 15 - OxyBand Research Background

OxyBand Dressing Accelerates Wound Healing

unique topical oxygen modality applied to simple standardized wounds at atmospheric
pressure.

A number of methods exist for delivering topical oxygen, most of which requires
either oxygen tanks, battery or AC-powered generators, chemical generation, or

TM
oxygenated solutions/foams. The key feature of the OxyBand is that it supplies
oxygen from the oxygen reservoir continuously to a wound as needed for multiple days

within a simple occlusive wound dressing. The OxyBand is a bi-layer wound dressing
TM
pre-filled with oxygen designed to maximize the oxygen saturation in the wound fluid.
TM
Driven by the diffusion gradient, the OxyBand raises and maintains the dissolved
oxygen (PO2) levels in the wound fluid, replenishing the wound with oxygen as it is
consumed.

Herein we report findings from two clinical studies conducted using OxyBand .
TM
TM
The efficacy of the OxyBand wound dressing (containing 95% oxygen) on
standardized laser burns was compared to a standard polyurethane wound dressing

(Tegaderm ). In a double-blind experiment, the efficacy of OxyBand TM to accelerate
TM
wound healing as measured by re-epithelialization of standardized laser burn wounds

was compared to an identical placebo dressing containing 21% oxygen.

METHODS:

Dressings

OxyBand Wound Dressing. The OxyBand TM (OxyBand Technologies, Inc) is a FDA
TM
510(k) cleared wound dressing for continuous delivery of oxygen into the wound for 5

days. The bi-layer wound dressing comes pre-filled with high levels (95+5%) of oxygen

between the layers. An open cell foam spacer maintains the shape of the reservoir.

4