Page 26 - OxyBand Research Background

OxyBand Dressing Accelerates Wound Healing

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OxyBand treated wounds compared to treatments using a standard of care
polyurethane or placebo control dressings are related to the specific oxygen delivery

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modality of the OxyBand dressings. Thus, OxyBand is a simple to use wound
dressing that provides potential benefits for various types of acute and superficial
wounds, including post aesthetic procedures. Further studies should be considered to

expand the application of this useful oxygen delivery technology in wound care including

larger and deeper wounds, as well as chronic wounds.

Acknowledgement: This investigation was conducted as a result of the inspiration of
Dr. T.K. Hunt’s pioneering and continued work on the beneficial effects of oxygen and

wound healing.

References:

Whitney, JD. Physiological effects of tissue oxygenation on wound. Heart & Lung. 1989;
18 (5):466-474.

Hopf HW, Gibson JJ, Angeles AP et al. Hyperoxia and angiogenesis. Wound Repair
Regen. 2005; 13(6):558–564.

Gordillo GM and CK Sen. Revisiting the essential role of oxygen in wound healing. Am J
Surg. 2003; 186:259-262.

Rahat MA, Marom B, Bitterman H et al. Hypoxia reduces the output of matrix
metalloproteinase-9 (MMP-9) in monocytes by inhibiting its secretion and elevating
membranal association. J Leukocyte Biol. 2006; 79:706-718.

Prockop DJ, Kaplan A, and Udenfriend S. Oxygen-18 studies on the conversion of
proline to collagen hydroxyproline. Arch Biochem BioPhys. 1963; 101:499.

Niinikoski J. Effect of oxygen supply on wound healing and formation of experimental
granulation tissue. Acta Physiol Scand Suppl. 1969; 334:1-72.

Hunt TK and MP Pai. The effect of varying ambient oxygen tensions on wound
metabolism and collagen synthesis. Surg Gynecol Obstet. 1972; 135:561-567.

Winter, GD. Oxygen and epidermal wound healing. Adv Exp Med Biol. 1977; 94:673-
678.

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